Evaluation of Immune Response to Measles Virus Antigen
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 2
Abstract
Increasing of measles infection cases in last few years is an important issue, which must be dealing with to assess the reasons. Immunizing lab animals with measles vaccine to is a better way understanding of vaccine-induced immune responses against measles vaccine. The current study is done investigated the phagocytosis index and the titer of specific antibody in response to measles vaccine measured by HI test in rabbits who received the vaccination to estimate the immune status after vaccination. Our study revealed that the rabbits subjected to the vaccine demonstrated an increase of 4-fold antibody concentration and increase in phagocytosis index (55.2, 59.8, 53.7, 51.5, 41.7)% after 14 days from immunization with the antigen comparing to the control. These results showed that the live attenuated measles vaccine is efficient. The aim is to evaluate the immune status after vaccination with measles virus, by calculating the phagocytosis index and the titer of specific antibodies produced because of stimulation the immune system to measles vaccine, to evaluate the effectiveness of the vaccine.
Authors and Affiliations
Layla Fouad Ali, Anas Felah, Noorkhan Bawa, Maryam Arkan
Keywords
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- EP ID EP394502
- DOI 10.9790/3008-1302025762
- Views 71
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