Evaluation of Leukocytes and Neutrophils, Markers of Inflammatory Syndrome in Preeclampsia
Journal Title: Applied Medical Informatics - Year 2010, Vol 27, Issue 3
Abstract
[i]Introduction[/i]: In pregnancies with preeclampsia, there is a generalized inflammatory response, which is much more intense than in normal pregnancy. [i]Aim[/i]: To evaluate leukocytes and neutrophils in the serum of pregnant women with preeclampsia and to compare these values to normal pregnancy. To investigate a possible relation between the detected values and the severity of preeclamptic syndrome. [i]Material and method[/i]: A transversal study was performed in three groups of patients: group 1 (preeclampsia), group 2 (normal pregnancy), group 3 (control). The samples were processed using a multichannel automated hematology analyzer – ACCOS 319. The results obtained were processed by descriptive and comparative statistical methods. [i]Results[/i]: A significant increase in leukocyte and neutrophil values was found in preeclampsia compared to normal pregnancy. Also, for group 2 (PE), there was no correlation between the number of leukocytes, neutrophils, respectively, and SBP and uric acid values, but a significant correlation was found between the studied inflammatory markers and DBP values. [i]Conclusions[/i]: Leukocyte and neutrophil values can be considered markers of the inflammatory syndrome present in preeclampsia. These parameters were positively correlated with DBP values.
Authors and Affiliations
Dan MIHU, Lavinia SABĂU, Nicolae COSTIN, Răzvan CIORTEA, Mihaela OANCEA, Andrei MĂLUŢAN
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