Evaluation of nucleic acid testing for blood donors: One year study

Abstract

Aims: Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory medicine. Investigations of transfusion-transmitted infections (TTI), especially hepatitis viruses and acquired immunodeficiency virus, are essential in all blood bank policies. Several methods were applied to screen blood products for hepatitis B and hepatitis C viruses and acquired immunodeficiency virus. Methods: Blood donor's samples for one year were collected and examined for hepatitis viruses and acquired immunodeficiency virus by using serological and nucleic acid testing (NAT). Results: Comparative study showed that NAT is more specific than serologic screening testing for both hepatitis C virus and acquired immunodeficiency virus. However, NAT and serological tests are required to increase the safety of blood components from hepatitis B virus transmission. Conclusion: This study is an attempt to evaluate the effectiveness of introducing NAT for examination of blood components. National-wide study is required to evaluate the policy of blood screening program.

Authors and Affiliations

Hussain Al- Turaifi

Keywords

Related Articles

Induced pluripotent stem cells in infections

Aims: Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory me...

Hepcidin testing; establishing reference values for the Namibian blood donor population

Aims: Anemia is a global health concern affecting billions of people worldwide. The diagnostic approach to iron deficiency anemia could be streamlined in an attempt to increase diagnostic sensitivity and to reduce uncert...

Study on the effectiveness of transfusion program in dengue patients receiving platelet transfusion

Aims: Dengue infection is a global health problem affecting an estimated population of 50–100 millions every year. Thrombocytopenia is an essential diagnostic criteria. Platelet transfusion is given in those patients who...

Prevalence of weak D phenotype among D negative C/E+ blood donors in Morocco

Aims: Determination of D variants is important for selection of blood products and to prevent anti-D-related hemolytic disease of the fetus and newborn. The prevalence of weak D phenotypes varies significantly among diff...

Comparative study of two automated pre-transfusion testing systems (microplate and gel column methods) with standard tube technique

Aims: Clinically significant antibodies may become undetectable and still provoke transfusion reactions. Hemolysis has been reported among transfusion recipients with anti-Kidd that was undetectable by gel column but det...

Download PDF file
  • EP ID EP209968
  • DOI 10.5348/ijbti-2015-18-OA-4
  • Views 139
  • Downloads 0

How To Cite

Hussain Al- Turaifi (2015). Evaluation of nucleic acid testing for blood donors: One year study. International Journal of Blood Transfusion and Immunohematology, 5(2), 19-25. https://europub.co.uk./articles/-A-209968