Evaluation of some natural gums as sustained release carriers in the manufacturing of tablets
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 3
Abstract
In the present investigation three natural gums namely gum karaya, gum tiruman and gum olibanum were evaluated as sustained release carriers for indomethacin. A comparative evaluation of the three natural gums is made. These three natural gums have not been investigated earlier. The three gums are available abundantly in the forests of eastern ghats. The genuine sample of the gums are supplied by the Girijan Corporation, Visakhapatnam. Indomethacin was included in the study in a model drug that requires controlled release because of its short biological half-life of 4.5 hours and also to reduce its G.I. side effects majorly peptic ulceration with bleeding.
Authors and Affiliations
Md. Bala Pasha, N. Ramarao
Keywords
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