Evaluation of some natural gums as sustained release carriers in the manufacturing of tablets
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 3
Abstract
In the present investigation three natural gums namely gum karaya, gum tiruman and gum olibanum were evaluated as sustained release carriers for indomethacin. A comparative evaluation of the three natural gums is made. These three natural gums have not been investigated earlier. The three gums are available abundantly in the forests of eastern ghats. The genuine sample of the gums are supplied by the Girijan Corporation, Visakhapatnam. Indomethacin was included in the study in a model drug that requires controlled release because of its short biological half-life of 4.5 hours and also to reduce its G.I. side effects majorly peptic ulceration with bleeding.
Authors and Affiliations
Md. Bala Pasha, N. Ramarao
FORMULATION AND IN-VITRO EVALUATION OF ORNIDAZOLE GASTRORETENTIVE TABLETS BY USING LOW DENSITY SWELLABLE POLYMERS
Gastro retentive drug delivery systems have shown to be of better significance in controlling release rate for drugs having site specific absorption. The present study was an attempt to develop floating tablets of ornid...
Drying of agriculture products using hot air oven and microwave method
Drying, an ancient process to preserve foodstuffs. Hot air drying may lead to produce dried products with more than one year shelf life. However the quality of oven dried products is less than the origin products. The a...
Adding of Malts in Order to Prepare Suitable Raw Material for Baking and Beer Industries
Malting is a complicated method includes soaking, sprouting, drying in controlled conditions of temperature and moisture. Diastatic power decrease significantly when adding barley. The amounts of barley-wheat protein ar...
Phytochemical evaluation of Vitex leuocoxylon, vitex negundo and vitex trifolia
In the present study, an attempt was made to investigate phytochemical evaluation of Vitex leuocoxylon, Vitex negundo and Vitex trifolia The crude drug powder extracts of the leaves of the above plants were taken for t...
Phytochemical screening of ethanolic extract of Passiflora foetida( Linn) and medicinal importance
India is enriched with many medicinal plants. Passiflora foetida is one of among such medicinal plants. The secondary metabolites present in medicinal plants are used for the treatment of many diseases. The secondary m...