Formulation and Evaluation of Cefixime Trihydrate Dispersible Tablets
Journal Title: International Journal of Trend in Scientific Research and Development - Year 2019, Vol 4, Issue 1
Abstract
Therapeutically active ingredients like tablet and capsule are conventional pharmaceutical dosage forms for manufacture, storage and ensure dosage uniformity. However, this dosage forms like capsules and tablets, often present ingestion problems such as difficulty in swallowing for the debilitated patients, particularly for paediatric and geriatric populations. This may result in a high incidence of non compliance and ineffective therapy, which may prove to be fatal in case of serious conditions. Suspension dosage forms could solve this problem, but they have other associated drawbacks like lower physical and chemical stability and high cost of manufacturing. Suspensions are also inconvenient to carry while travelling and also involve the risk of inaccurate measurement and dosing. Thus, there is a need for oral pharmaceutical composition, which can be taken orally without the need of swallowing it and act as a viable substitute for suspensions. Accordingly, provided are water dispersible tablet compositions, which can either be chewed or can be readily dispersed in water before oral administration. One of the key requirements of water dispersible tablet is they could dissolve in an aqueous medium within a short time period for example, less than three minutes, to form a smooth suspension without any coarse lumps. Dispersible tablets provide advantages of both tablets and liquid formulations. These are convenient to carry, easy to manufacture and more stable dosage forms. Ms. Remya S. B | Dr. Subash Chandran M. P | Ms. Aparna P "Formulation and Evaluation of Cefixime Trihydrate Dispersible Tablets" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-1 , December 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29627.pdf Paper URL: https://www.ijtsrd.com/pharmacy/pharmaceutics/29627/formulation-and-evaluation-of-cefixime-trihydrate-dispersible-tablets/ms-remya-s-b
Authors and Affiliations
Ms. Remya S. B | Dr. Subash Chandran M. P | Ms. Aparna P
Keywords
Related Articles
- EP ID EP685742
- DOI -
- Views 124
- Downloads 0
Macroeconomic Variables and Manufacturing Sector Output in Nigeria
Management of macroencomic variables has been noted as instrumental to a well performing manufacturing sector. This study thus examined the effect of macroencomic variables on the manufacturing sector in Nigeria within a...
Toward Cloud Network Infrastructure Approach Service and Security Perspective
The primary goal of the paper is to support a complete integrated solution for a single communication platform providing cloud services to end users. The paper presents a literature review of cloud computing concepts and...
Salesforce – The Future of CRM
Salesforce is one of the popular CRM Platform which is used to manage customers and their relationships with an organization. It helps businesses to connect with customers by using cloud technology. It also provides flex...
Strong Regular L-Fuzzy Graphs
In this paper, the notion of regular and strong regular L-fuzzy graph is introduced. The conditions for strong regularity of L-fuzzy graphs on cycle and star graph are derived. R. Seethalakshmi | R.B. Gnanajothi"Strong R...
Effect of Service Quality Gaps in Hospital Industry
Quality is considered as one of the imperative factors. In hospital industry patient is a consumer of the hospital whose fulfillment must be taken note. The fulfillment of the patient has relied upon the service executio...