Frequency of Kell Blood Group Antigen in Voluntary Blood Donors
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 4
Abstract
Background: The data on incidence of antigens of various blood groups in the local donor population helps in routine blood transfusion practices of a blood transfusion centre. It is important to know the frequencies of the various antigens when dealing with patients who have developed multiple alloantibodies. This information is necessary to predict the availability of blood units that lack the corresponding antigen(s). The current practice of providing compatible blood to patients in such cases in India is still reliant upon random cross matching of available units in the inventory. Aim: To study the prevalence of Kell antigen in the voluntary blood donors with a view to generate blood bank data for constitution of panel of blood donors for multipurpose utilities. Materials and methods: A prospective study was carried out on 3014 healthy blood donors from April 2016 to Nov 2016 at our blood bank. Donors were grouped and typed for ABO and Kell antigen. Statistical analysis was carried out using Microsoft excel software. Incidence was given in proportion with 95% confidence interval. Results: The frequency of K antigen was 2.92%. Conclusion: Database for antigen frequency in local donor population helps to provide antigen negative blood unit to patients with multiple alloantibodies, minimize alloimmunization rate, and thereby improve blood safety.
Authors and Affiliations
Dr. Rashi Pachaury
Keywords
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