Fungal Profile of Occular Infection in Patients Attending In a Tertiary Care Hospital
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 4
Abstract
Aim and objective: To identify the fungal etiology of Ocular infections in patients attending Ophthalmology department from the period Nov 2010 to Sep 2011 at Navodaya Medical College Hospital and Research Centre, Raichur. Methods: 102 patients attending Ophthalmology OPD/IPD in Navodaya Medical College Hospital and Research Centre were analysed from Nov 2010 to Sep 2011. Using predefined inclusion and exclusion criteria, samples were collected according to the standard protocol. These were cultured for microorganisms (fungal) and were identified. Results: Out of 102 samples studied, 75 samples had growth and the isolation rate. only 23(26%) was fungal growth. KOH wet mount examination showed high specificity of 98.73% and PPV of 90.91% with very significant p value of < 0.0001. The most common fungal isolate were Fusarium spp (30.43%) followed by Aspergillus spp (26.04%). Conclusion: Fungal etiology was mostly associated with corneal infections. Direct microscopic examination is an essential tool in the diagnosis of fungal infections. A simple and rapid KOH wet mount examination early during the disease result in significant progress of the disease in initiating early and specific therapy.
Authors and Affiliations
Namitha Bn1, Mahalakshmi .
Keywords
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