Gene Therapy: The New Weapon Against Diseases Until there Difficult to Overcome, Some Current Facts of Gene Therapy and Cases of Sickle Cell Anemia
Journal Title: Journal of Clinical and Medical Research - Year 2020, Vol 2, Issue 4
Abstract
Sickle cell anemia is an inherited genetic disease that affects the hemoglobin chains of red blood cell hemoglobin, carrying oxygen-less well through the body. It is a rare disease; however, it is the most widespread genetic disease in the world and especially widespread in sub-Saharan Africa. It causes anemia, painful seizures that affect several organs; it is also called sickle cell anemia, this disease results in a deformation of red blood cells in the form of sickle or a crescent moon, which prevents normal circulation in the blood vessels. This will cause blood flow to be blocked. It is a disease that is geographically concentrated in certain areas such as Africa, India, Brazil, the Mediterranean Basin, but it is currently found everywhere because of mass migration and has been considered since 2008 by United Nations as a public health priority. Sickle cell disease affects black people and accounts for 50% of deaths in childhood. A 2005 study published in The Lancet estimated that 4.4 million people worldwide are affected by the disease. Research is trying to improve the treatment of sickle cell disease, too, through gene therapy, which has already been proven today. Sickle cell anaemia is the most common genetic disease, yet it is still little known to the public. According to the United Nations, sickle cell anemia is the most responded genetic disease in France with more than 12,000 people affected and recognized as a public health priority. Sickle cell disease is still poorly known to the public and patients with this genetic disease do not benefit from optimal management: IGNORANCE? In France, DOMs are considered to be areas of risk, which is why screening for the disease is mandatory at birth for all children born in the DOM as well as for babies born in the metropolis but whose parents are from Overseas.
Authors and Affiliations
Carolle Laure MateneFongang*
Keywords
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- EP ID EP708401
- DOI https://doi.org/10.37191/Mapsci-2582-4333-2(4)-042
- Views 60
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