GREEN SYNTHESIS OF SILVER NANOPARTICLE FROM LEAF EXTRACT OF AEGLE MARMELOS AND EVALUATION OF ITS ANTIBACTERIAL ACTIVITY
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 6
Abstract
Objective: The synthesis of metal nanoparticle is a growing area of research in modern material science and technology. Utilization of the silver nanoparticles in the field of biomedical nanotechnology and nanomedicines is rapidly growing because of their antimicrobial, anticancer, antioxidant property and less toxicity. Nanoparticles are synthesized by chemical methods, but are not eco-friendly. The objective of the study is to develop a fast, eco-friendly and convenient method for silver nanoparticle synthesis.Methods: In this method utilization of the reducingproperty of Aegle marmelos leaf extract was done for synthesis of stable silver nanoparticles. Characterization of the metal nanoparticles was carried out by UV- Vis spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), X-ray Diffraction microscopy (XRD), Energy Dispersive X-ray spectroscopy (EDX) and zeta potential analysis.Results: This result showed the average particle size of 15 -30 nm and spherical structure of stable silver nanoparticles. Green synthesized nanoparticles tested for its antibacterial activity by the well diffusion method. Silver nanoparticles had shown a more inhibitory effect against Streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa than Staphylococcus aureus and Aeromonas hydrophila at 25, 50 and 100 µg/ml concentrations.Conclusion: This study is recommends the use of Aegle marmelos leaves for the synthesis of silver nanoparticles and can be applied as an antimicrobial agent.Â
Authors and Affiliations
Sunita Patil, Rajeshwari Sivaraj, P. Rajiv, Rajendran Venckatesh, R. Seenivasan
Keywords
Related Articles
- EP ID EP578682
- DOI -
- Views 67
- Downloads 0
METABOLIC SYNDROME ASSOCIATED COMPLICATIONS
Metabolic syndrome (MetS) is characterized by a cluster of disorders like obesity, insulin resistance, glucose intolerance, hypertension and dyslipidemia. All these disorders are responsible for the development of second...
METFORMIN IN THE PREVENTION OF METABOLIC SYNDROME ASSOCIATED WITH INITIATION OF ATYPICAL ANTIPSYCHOTIC THERAPY IN ADOLESCENTS AND YOUNG ADULTS - A RANDOMIZED, OPEN LABELLED, SINGLE CENTERED STUDY
Objective: The aim of the study was to evaluate the effectiveness and safety of Metformin along with Risperidone to prevent antipsychotic-induced metabolic syndrome in first-episode schizophrenia patients.Methods: This w...
A GLOBAL COMPARISON AND ANALYSIS OF NEURAMINIDASE H1N1 STRAIN OF INFLUENZA A
Objective: To evaluate the variation of neuraminidase (NA) protein from various H1N1 strain for drug designing.Methods: In this study we have used 12 sequences of NA protein from various countries, retrieved from Uniprot...
DEVELOPMENT OF HYDROPHILIC MATRIX TABLET OF CARBAMAZEPINE USING 33 FULL FACTORIAL EXPERIMENTAL DESIGNS
Objective: The study aims at developing the hydrophilic matrix tablet of carbamazepine (CBZ) using an optimization technique. The purpose of the study was to develop the hydrophilic matrix dosage form using the combinati...
ASSESSMENT EFFECT OF ALOE VERA, AZADIRACHTA INDICA AND MORINGA OLEIFERA AQUEOUS EXTRACTS ON CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
Objective: This experiment aims to investigate the hepatotherapeutic effect of Aloe vera (AV), Azadirachta indica (N), and Moringa oleifera (MO).Methods: Eighty albino rats have been divided into ten groups. The first gr...