Haematotoxicity as an issue for toxicology of chemical substances and some approaches to resolve it
Journal Title: Український журнал сучасних проблем токсикології - Year 2017, Vol 77, Issue 1
Abstract
Haematological studies allowing to assess unfavourable effects on blood system and to develop preventive measures for the reduction of the risk of xenobiotic influence on human health are an indispensable part of complex assessment of toxic properties of pesticides upon hygienic rating. In spite of this fact, publications on the development of haematological diseases in human as the result of contact with pesticides regularly occur in the literature. This article summarises and provides some of the peculiarities of experimental studies on the detection of haematological effects ofxenobiotics, where the main unfavourable effects that allow assessing potential hazard of the chemical substances by the criterion “haematotoxicity” are emphasised. Approaches to the deep exploration of the effect of pesticides on the blood system and interpretation of the obtained results have been established.
Authors and Affiliations
V. G. Shulyak, P. G. Zhminko
Keywords
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