HEALTH-RELATED QUALITY OF LIFE OF A PATIENT FOLLOWING NEUROSURGERY ON GLIOBLASTOMA MULTIFORME (GBM)
Journal Title: Acta Neuropsychologica - Year 2018, Vol 16, Issue 3
Abstract
Health-related quality of life (HRQoL) plays a role as a patient-centered meaningful endpoint, assessing the direct clinical benefit for a patient. The inclusion of HRQoL measurements in a glioma patient may provide important data to inform clinicians on treatment decision-making. The aim of the study was to evaluate cognitive decline and HRQoL in the clinical care of a patient following neurosurgery on of glioblastoma multiforme (GBM).<br/><br/>A 69-year-old female developed malignant brain glioma in the right temporal-occipital area; this being confirmed by CT and MR study and neuropathological findings. She had complained of headaches, dizziness, nausea, vomiting as well as attention and memory loss, and anxiety, sadness and a slowing down in the performance of daily activities. The symptoms rapidly became worse and she was referred to a neurosurgery department for consultation. She was successfully neurosurgically operated on. She was examined with the use of ne uro psycho logical tests three times: the first examination was conducted before the neurosurgical operation, the second two weeks after, and the third half year after the neurosurgical operation. In the first examination by the standard Polish version of the Mindstreams™ Interactive Computer Tests disturbances for all the tested cognitive functions occurred. The greatest changes were to occur however in the areas of visual-spatial functions. attention, executive functions and memory. In the second test, a return to the norm was achieved for the disturbed cognitive and executive functions. In the third examination (half a year after the neurosurgical operation), the cognitive and executive functions were still not bad, but had slightly decreased. Similar trend was observed in HRQoL. A significant difference in the health profile between the 1 st and 2 nd as well as between 1 st and 3 rd examination was detected for the eight SF-36 domains - HRQoL was improved. While only slight but no significant changes occurred between 2 nd and 3 rd examination. HRQoL was still not bad, but had slightly decreased.<br/><br/>The patient after the neurosurgical operation of glioblastoma multiforme (GBM) is capable of carrying out daily activities, but shows some level of reduced complains for functional capacity, pain, general health and vitality, emotional and social functioning for mental health which has led to the impaired HRQoL.<br/><br/>
Authors and Affiliations
Rafał Morga, Marek Moskała, Dariusz Adamek, Jolanta Góral-Półrola, Izabela Herman-Sucharska, Maria Pąchalska
Keywords
Related Articles
- EP ID EP411506
- DOI 10.5604/01.3001.0012.7452
- Views 146
- Downloads 0
NEUROPSYCHOLOGICAL TESTING OF AD/HD SUBTYPES AS AN INDICATOR FOR NEUROMETRICS AND THERAPY: CURRENT STATE AND FURTHER CONSIDERATIONS
The research presented in this chapter reflects some current trends in neuropsychological research on AD/HD children, with the goal of exploring the structure of the mental deficits that shape the clinical picture. The p...
Badanie EEG wraz z potencjałem P300 jako metoda do sprawczego różnicowania pacjentów z uwarunkowaniem genetycznym i środowiskowym uzależnienia od alkoholu
Charakterystyka elektrofizjologiczna alkoholików, w postaci amplitudy P300 w zakresie potencjałów indukowanych (ERP), jest związana z wysokim ryzykiem alkoholizmu u potomstwa i uważa się ją za biologiczny endofenotyp pre...
THE KING-DEVICK TEST: AN INDICATOR OF LONGER-TERM COGNITIVE EFFECTS POST-CONCUSSION
Background: The King-Devick test (K-D) was introduced in 2011 as a quick, easy and cost-effective way to screen for a concussion. Relying on differences in visual scanning between a baseline and post-injury examination t...
IDENTITY DISTURBANCES IN A PATIENT WITH SEVERE TRAUMATIC BRAIN INJURY: A CASE STUDY
Background Patients aroused from a long -term coma after severe TBI oftenexhibit identity disorders, which are connected with discontinu-ity of the life story, and in consequence with the existence of two different autob...
INDIVIDUAL HAPPINESS IN TERMS OF PROCESS NEUROPSYCHOLOGY
[b][/b][b]Background. [/b]The aim of this work was to discover what happiness means to a sample of healthy persons as compared to persons with brain and spinal injury resulting from an automobile accident. [b]Material/Me...