Heart Failure with Preserved Ejection Fraction: A Study of Clinical Profile in Indian Patients
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 6
Abstract
Introduction: Heart failure is growing epidemic condition and nearly half of the patients have preserved ejection fraction (EF>50%).However, study regarding prevalence, and etiologies of diastolic heart failure are sparse for Indian population. So, we carried out a study to determine demography and clinical profile of heart failure patients with preserved ejection fraction. Material and Methods: This was an observational Study. Patients, who presented with clinical features of heart failure according to Framingham Criteria, with Left ventricular EF > 50%, from 1st September 2015 to 30th May 2018, were included in the study. Patients underwent thorough physical examination, routine laboratory testing, and other relevant investigations A detailed analysis of demography, and clinical profile, was performed. Statistical analysis was done using percentage analysis. Results: Out Of 812 patients, 496 (61.08%) were females and 316 (38.91%) were males. The mean age of patient was 50.52 (±15.81) years with range of 35 to 92 years. Hypertension (78.94%) was the most common associated risk factor followed by obesity (56.03%), dyslipidemia (48.02%), diabetes mellitus (47.78%) and smoking (34.48%). Dyspnea (97.78%) was the most common presenting symptom followed by PND (55.78%), fatigue (51.10%) and cough (38.05%). Most of the patients (55.04%) had Grade 1 Left ventricular diastolic dysfunction. 58.12% patients had associated pulmonary arterial hypertension. Conclusion: Heart failure with preserved ejection fraction (HFPEF) was more in female and hypertension was the most common associated risk factor in Indian population.
Authors and Affiliations
Mayank Jain, Priyanka Kiyawat, Surabhi Kiyawat
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