Hemodynamic changes and post-operative complications with use of caudal bupivacaine and bupivacaine-dexmedetomidine combination for post-operative analgesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 5, Issue 1
Abstract
Background: Caudal anaesthesia is a commonly performed regional block in children for abdominal and lower limb surgeries. The use of adjuncts like Dexmedetomidine can effectively help in reduction of the dose and an increase in duration of action of the local anaesthetic agent like bupivacaine. Aim: To study addition of Dexmedetomidine to bupivacaine with regards to hemodynamic changes and post-operative complications. Material and Methods: A total of 60 patients of 2-10 years of age posted for routine infraumbilical surgerieswere randomly divided in to two groups. Group A- (Control group) received 0.25% Bupivacaine. Group B - (Study group) received 0.25% Bupivacaine + 1μg/kg Dexmedetomidine. Haemodynamic parameters in the form of pulse rate, blood pressure, SpO2, respiratory rate were observed. Results: The difference between the two groups for change in mean arterial pressure was statistically significant, but the patients were haemdynamically stable. Two patients from group A and one patient from group B had vomiting in the postoperative period. While two patients from both group A and group B complained of failure to pass urine at 6 hrs. Conclusion: The addition of dexmedetomidine in the dose of 1μg/kg to 0.25% bupivacaine for caudal blockade significantly prolongs the duration of analgesia without any significant hemodynamic changes and is safe for use in paediatric patients.
Authors and Affiliations
Attar Tausif, Kamble Raviraj, Agrawal Pushpa, Kulkarni Vaishnavi
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