Hemophagocytic Syndrome Associated with Herpes Virus 8 and Multicentric Castleman Diseases in a HIV-Negative Patient
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2017, Vol 7, Issue 4
Abstract
The Hemophagocytic syndrome (HS) is a very rare and aggressive disorder characterized by strong immunological activation of the mononuclear phagocyte system sometimes triggered by viral infections such as Epstein-Barr Virus. Castleman disease is a heterogeneous group of lymphoproliferative disorders associated in some cases with the human immunodeficiency virus (HIV) and human Herpes Virus 8 (HHV-8). The association of HHV-8, Multicentric Castleman Disease (MCD) and Hemophagocytic Syndrome is extremely rare. There are very few reported cases in literature, mostly in HIV positive elderly patients with fatal prognosis.We report a case of Hemophagocytic syndrome, HHV-8 and MCD on an HIV negative young adult. J Microbiol Infect Dis 2017; 7(4):202-206
Authors and Affiliations
Arturo González Raya, Eva Martín Salido, Miguel Cantero Sánchez, Gonzalo Callejón Martín, María L. Hortas Nieto
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