HIGH PERFORMANCE NANOPARTICLE FLUID SUSPENSIONS (NANOFLUIDS): A FUTURE OF PHARMACEUTICAL NANOTECHNOLOGY
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2014, Vol 6, Issue 4
Abstract
Pharmaceutical nanotechnology is evolved as a powerful tool for pharmaceutical chemist and formulation scientists. It has given a new direction to pharmaceutical and drug discovery research. Nanofluid technology which deals with nanofluids has provided an ultimate engineering solution for heat transfer application and automotive application in different industries. Nanofluids are engineered colloidal suspensions of nanoparticles in a base fluid. The nanoparticles used in nanofluids are typically made up of metals, oxides, carbides or carbon nanotubes. Common base fluids include water, ethylene glycol and oil. Preparation of nanofluids may be done by one step, two step method, chemical approach or laser ablation. The stability of nanofluids can be enhanced by different means such as addition surfactants, surface modification technique, pH control and ultrasonic agitation. Nanofluids are well known for their applications in engineering field, many researchers have also reported their use for different biological, medical and biomedical applications. Considering the tremendous growth of pharmaceutical nanotechnology with respect to drug discovery, formulation and development of nanoparticulate novel drug delivery systems, it is expected in coming years that high performance drug nanoparticle fluid suspensions (nanofluids) will begin a new era of formulation research. This review article summarises method of preparation, characterization, stability, recent research and applications of nanofluids. It also identifies future scope of nanofluid technology for applications in pharmaceutical field.
Authors and Affiliations
M. S. Deodhar, A. R. Shirode, V. J. Kadam
Keywords
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