Histopathological Findings in Gastrointestinal Perforations - A study of 100 cases
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 1
Abstract
Introduction There are large numbers of cases where gastrointestinal perforations occur in stomach, small gut and large gut but without histopathological examination of biopsy material, it is not possible to reach to any conclusion. There are various causes of gastrointestinal perforation. The most common cause of perforation are enteric, tuberculosis, amoebiasis and traumatic injury. Material & Methods The study is done on 100 specimens received in the Govt Medical College, Department of pathology, Patiala. Gross findings and microscopic features were recorded. The tissue specimens were fixed and processed and Paraffin sectioning was done followed by Haematoxylin and Eosin staining. The sections were then examined. Results Out of which 100 specimens of GI perforations were studied. Most of the samples (55) were in the form of small pieces from the margins of perforation followed by 34 resected gut specimens and 11 samples were of burst appendix. Most of the patients were males, with male to female ratio as 4:1. As far as site is concerned the most common location of perforation was ileum followed by stomach and least common were Meckel’s diverticulum and rectal perforations. Conclusion It was concluded that histological examination of biopsies from the perforation site plays a key role to reach to a definite diagnosis, supported by clinical presentation and serological tests.
Authors and Affiliations
Ramandeep Kaur
Keywords
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