Histopathological Study of Malignant Neoplastic Lesions of Breast
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Breast cancer is a leading cause of mortality and morbidity among women worldwide.The high mortality associated with breast cancer is linked to the aggressiveness of the tumor which depends to a large extent on the histopathological subtypes. It is a heterogeneous disease, comprising multiple entities associated with distinctive histological and biological features, clinical presentations and behaviours and responses to therapy. Histological grade has been incorporated in multiple, validated, prognostic algorithms to determine breast cancer therapy, such as the Nottingham PrognosticIndex. Many studies have tried to identify prognostic factors for breast cancer with nodal status and histopathologic subtypes featuring prominently as prognostic indices. This study was a retrospective analysis of all consecutive breast cancer specimens study from January 2011 to September 2016 biopsysubmitted to the Pathology Department of Hassan Institutional Medical Sciences, Hassan. Prominent histomorphological features, grading, typing, Lymphovascular invasion, lymph node involvement and involvement of the surgical margins were studied in detail. The aim of this study was to know the age incidence patterns for different histopathologic types of carcinoma and to know the involvement of deep resected margin and number of lymph nodes by malignant cells.
Authors and Affiliations
Udasimath Shivakumarswamy
Keywords
Related Articles
- EP ID EP471102
- DOI 10.21088/ijprp.2278.148X.6417.18
- Views 79
- Downloads 0
Seroprevalence of Transfusion Transmitted Infections among Voluntary Blood Donors in a Rural District Hospital
Background: Transfusion transmitted diseases continues to be a major threat for safe transfusion practices. Lack of study from this part of the country propelled us to conduct this study. Materials and Methods: This was...
Lycopodiumclavatum and Conium Maculatum effect on Hearts of Mice Infected with Trypanosomacruzi
Chagas disease is a potentially fatal condition that presents high capacity to infect cardiac muscle cells and frequently evolves to dilated cardiomyopathy and congestive heart failure. The treatments available nowadays...
Spectrum of Pulmonary Histopathological Lesions: A Study of 191 Medicolegal Autopsies
Background: Autopsy is an important and most useful way to find out the condition of internalorgans in which a thorough examination is performed on a body after death to evaluate disease or injury thatmay be present and...
Haematological Parameters in PLHIV with Utility of Absolute Lymphocyte Count (ALC) As Surrogate Marker for CD4 Count: A Study from India
Context: Since it’s first report in 1982, HIV has emerged as a major pandemic. Haematological abnormalities are among the most common clinicopathological manifestations of HIV infection including impaired haematopoiesis,...
Knowledge, Attitude and Perception amongst College Students Regarding Blood Donation
There is persistent shortage of active blood donors to meet the increased demand of blood in blood banks. The safety of blood with regard to the risk of transfusion transmissible infection is also an issue of utmost conc...