Hyperbaric Oxygenation in Treatment of Alcohol Withdrawal
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Abstract: The duration and severity of alcohol withdrawal is a great concern while treating alcohol dependent patients. Hyperbaric oxygen therapy (HBOT) has been used in few centers world over, for faster recovery of withdrawal symptoms. The present study aimed to undertake a preliminary study exploring this possibility. Thirty alcohol dependent patients were recruited in this study. They were divided into A: HBOT group (received hyperbaric oxygen therapy for 90 minutes) and B: non-HBOT group (received normobaric oxygen therapy for 90 minutes) using simple randomization technique. Withdrawal symptoms were assessed daily, using the Clinical Institute Withdrawal Assessment scale (CIWA-Ar). The data collected from the two groups were compared. Statistical analysis used was Independent two sample t test. When the two groups were compared, it was found that the mean period (in days) required for the control of withdrawal symptoms for the HBOT group was 3.72 and for the non-HBOT group was 9.03 and the difference was statistically significant (P = 0.0001). A better outcome among the HBOT group indicates that the effect of HBOT as an adjunct to the current detoxification regime, in the treatment of alcohol dependent patients is definitely worth consideration and stronger evidence can be brought out in a larger multicenter trial.
Authors and Affiliations
Geomy George Chakkalakkudy, Prashanth Varkey, James T Antony, Merin Poulose, Angel Abraham
Keywords
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