Abstract

We have conducted the present study to evaluate the effect of probioticated tomato juice (PTJ), probioticated carrot juice (PCJ), and their mixed juices (PCT) containing Lysinibacillus sphaericus on high-fat diet (HFD)-fed albino Wistar rats. Eight groups consisting of 6 rats each were designed in the experiments and orally administered the above probioticated juices (at 1–2 mL per rat) to HFD-fed rats for 28 days. This included a group maintained on normal control diet (NCD), HFD, and an experimental control group maintained using lovastatin (at 5 mg/kg body weight). After feeding the rats, the lipid profile of the blood serum was studied in all the eight groups. HFD-fed rats showed elevated lipid profile levels as compared to NCD-fed rats. Probioticated juices reversed the elevated lipid profile levels to near normal in HFD-fed rats. This hypolipidemic effect was more significant in PCJ-fed (2 mL/rat) groups than the other groups. On treatment with the PTJ, PCJ and PCT showed the lowering of body weights when compared to HFD group.

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