Identification and component analysis of triterpenoids in Monarda fistulosa L. and Ocimum americanum L. (Lamiaceae) aerial parts
Journal Title: ScienceRise: Pharmaceutical Science - Year 2018, Vol 0, Issue 3
Abstract
<p class="xfmc1">Despite the progress in the creation of synthetic drugs, herbal medicines do not lose their relevance nowadays. Triterpenoids are quite common in the plant world and exhibit a wide range of biological activity. Medicinal plants of the Lamiaceae family can accumulate mainly pentacyclic triterpenoids which demonstrate the anti-inflammatory, antioxidant, hepatoprotective, anticancer and antimicrobial properties. Nowadays a number of new, poorly-studied species of the family have been introduced in Ukraine, including Monarda fistulosa L. and Ocimum americanum L.</p><p class="xfmc1">The <strong>aim</strong> of this study was to identify the triterpenoids and to analyze the contents of their components in ethanolic extracts of M. fistulosa and O. americanum (Lamiaceae) aerial parts under the condition of their farming in West Podillya (Ukraine).</p><p><strong>Methods: </strong>foam test, sedimentation and color reaction were used to determine the presence of triterpenoids in plant material; high-performance liquid chromatography (HPLC) method was used to determine their components' content; determination was carried out on a liquid chromatograph Shimadzu LC 20 Prominence.</p><p><strong>Results</strong>. The presence of triterpenoids in M. fistulosa and O. americanum ethanolic extracts was proved by the reactions of identification and HPLC. Effective extraction of triterpene compounds from the investigated plants was achieved using 96 % and 70 % ethanol. The comparative HPLC-analysis showed significant differences in content of ursolic, euscaphic, tormentic and oleanolic acids, betulin and lupeol in the aerial parts of investigated species. The most abundant components of M. fistulosa and O. americanum herbs were the ursolic and euscaphic acids.</p><strong>Conclusions</strong>: It was identified the presence and evaluated the contents of 6 triterpenoids in M. fistulosa and O. americanum aerial parts. The obtained data can be used in the planning of pharmacological studies and in the chemotaxonomy of Lamiaceae family
Authors and Affiliations
Mariia Shanaida, Olena Golembiovska
Keywords
Related Articles
- EP ID EP526836
- DOI 10.15587/2519-4852.2018.135767
- Views 136
- Downloads 0
Investigation of food supplements with preservative e211 (sodium benzoate) using thin-layer chromatography
<p>Sodium benzoate is often chosen for the manufacture of liquid food supplements as preservative due to its antimicrobial effect against a large number of microorganisms. Permissible sodium benzoate amount in liquid foo...
Хромато-мас-спектрометричне дослідження низькомолекулярних аліфатичних, жирних та ароматичних кислот кореневища Veronica teucrium L.
<p><strong>Мета.</strong> Хромато-мас-спектрометричне визначення якісного складу та кількісного вмісту аліфатичних, ароматичних та жирних кислот у кореневищах Veronica teucrium L.</p><p><strong>Методи.</strong> Об’єктом...
Определение технологических параметров травы полыни Гмелина
<p>Своевременной задачей фармации является продолжение исследований наиболее часто используемого лекарственного растительного сырья, которое является перспективным для создания на его основе новых лекарственных средств....
Synthesis of potential antiexudative preparations for 2-((4-amino-5-(furan-2-il)-1,2,4-triazole-(4H)-3-yl)-sulfanyl)-N-acetamide series
<p><strong>Aim.</strong> Conduct the purposeful synthesis of new potential biologically active substances of derivatives of 2 - ((4-amino-5- (furan-2-yl) -1,2,4-triazol (4H) -3-yl) -sulfanyl) -N-acetamides and evaluate t...
The influence of indolinoren on kidney function in conditions of water and salt load
<p>Diuretics are widely used to correct kidney disorders. In turn, the ionic composition of food, mostly sodium ions, which directly affect the excretory function of the kidneys, can act as modulators of the action of di...