IgA Nephropathy – selected problems including older patients
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 2
Abstract
IgA nephropathy (IgAN) is a proliferative form of glomerulonephirits with massive residues of IgA in mesangium. Presently it is the most frequently diagnosed form of glomerulonephritis in the world. It constitutes from 25% to 50% of all histopathological identifications of kidney biopsy specimens. This frequency varies according to the world region, which could depend on both real differences in its occurrence and on utilizing different indications in biopsy or diagnostic criteria. IgAN is above all a condition of the young people, and the peak of falling ill is during their twenties and thirties. It does occur in older patients as well. It is believed that the advanced age may be one of the factors causing quicker progression of the kidney disease. In literature not much information can be found concerning IgA nephropathy in older patients. It may result from the fact that the basis for diagnosing glomerulonephrititis is kidney biopsy. However, in older patients reluctance to having a kidney biopsy performed is quite common, mostly due to fear of complications. In this paper available data concerning IgAN epidemiology was summarized, including both general population and the population of seniors. Moreover, the level of knowledge in regard to prognosis and the strategy of therapeutic actions while taking into account older patients’ population was discussed.
Authors and Affiliations
Beata Sulikowska, Jacek Manitius
Keywords
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