Imaging features and diagnostic value of optical coherence tomography angiography in buried optic disc drusen
Journal Title: Eye Science (Yanke Xuebao) - Year 2020, Vol 35, Issue 4
Abstract
[Objective:] To observe the imaging features and diagnostic value of optical coherence tomography angiography (OCTA) in buried optic disc drusen (ODD). [Methods:] A total of 13 patients (20 eyes) were diagnosed as buried optic disc drusen at Nanjing Medical University Eye Hospital from January 2017 to December 2018. The clinical data and the imaging features of OCTA were analyzed. [Results:] Fundus examination showed that the boundaries of the optic disc was unclear, disappearance of physiological depression, complicated with abnormal optic disc branch blood vessels, dilatation, increase and distortion changes and peripapillary hemorrhage, etc. B-mode ultrasound showed there was a locally hyperechoic bulge at the optic disc, and local calcification was hyperechoic. Fundus fluorescein angiography (FFA) showed that optic disc drusen with hyperfluorescence staining and no leakage. OCTA showed that the retina nerve fiber layer (RNFL) was thicker than normal and the size of the optic disc depression were different. B-scan showed that there was a small round hyperreflexes intraretinal, which appeared to be wrapped in cystic membrane with no blood flow signal inside. The blood flow density of radial peripapillary capillaries (RPC) was decreased in the ischemic region. After corresponding treatment, OCTA during follow-up showed that the hemorrhage was completely absorbed in four cases complicated with peripapillary hemorrhage, and the bulge of optic disc drusen had no change. [Conclusion:] Buried optic disc drusen has characteristic performance in OCTA. Multimode images can help to make a definite and differential diagnosis in clinic. Non-invasiveness and convenience are the greatest advantage.
Authors and Affiliations
Sha TIAN, Yue ZHAO, Jin YAO
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