ISOLATION AND IDENTIFICATION OF RNASE A FROM TESTIS THROUGH HPLC AND CHROMATOFOCUSSING
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Abstract From the previous studies it was clear that RNase A is present in pancreas and our new Finding includes that RNase that is similar to RNase A was also present in testis along with other RNases in the tissue. In chromatofocussing the peak was observed in fraction 5 of PI 9.6 and in HPLC it was present in all fractions of the column. The aim of present work is to isolate and identify RNase A through HPLC and chromatofocussing. From the results we conclude that RNase A is present in testis in addition to its presence in epidydymis .Future perspectives include finding of other RNases present in the testis and also further evaluation by other methods.
Authors and Affiliations
EswariBeeram. , Kamala Katepogu. , ThyagarajuKedam*
Keywords
Related Articles
- EP ID EP330683
- DOI -
- Views 100
- Downloads 0
RP-HPLC and chemometric assisted UV-spectrophotometric methods for simultaneous in vitro analysis of atrovastatin calcium, ezetimibe and fenofibrate in their pharmaceutical formulation
One RP-HPLC and two chemometric assisted UV spectrophotometric methods were developed and validated for the simultaneous in vitro analysis of Atrovastatin calcium (ATV), Ezetimibe (EZET) and Fenofibrate (FEN) in their ph...
PRESCRIBING PATTERN OF DRUGS IN PREGNANT WOMEN ATTENDING ANTENATAL OUTPATIENT DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL
Abstract Drug treatment during pregnancy presents a special concern. Pharmacoepidemiological studies can measure the extent of prescription and teratogenic drug use in pregnant women. Objective: To understand the prescri...
Optimization of fast dissolving aceclofenac tablets using factorial design
The Aceclofenac is available in tablets dosage form and is yet not official in any pharmacopoeia except B.P. Aceclofenac is practically insoluble in water and peak blood level rechease between 1.25 to 3 hrs after oral ad...
SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM: SOLIDIFICATION TECHNIQUES, DOSAGE FORM AND EVALUATION.
Abstract Low aqueous solubility is attributed to the low oral bioavailability is a major problem for formulation scientist as most of recent drugs are lipophilic in nature and their lower solubility and dissolution is a...
Anthelmintic activity of root of Benincasa hispida (Petha)
The present study was undertaken to evaluate anthelmintic activity of crude aqueous, Petroleum ether, chloroform and methanol extracts of Benincasa hispida (Petha) root using Pheretima posthuma as test worms. Single conc...