Laboratory and production investigations of insecto-acaricidal preparation “Ciflur”
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2018, Vol 32, Issue
Abstract
Introduction. Ticks and insects, which parasitize on animals cause anxiety, local irritation, inoculate the bioactive substances, and these arthropods are vectors and carriers of infectious agents. Reduction of treatment and prophylaxis effect of insecto-acaricidal preparation have explained by appearance of resistance in arthropods. Therefore, the search for protective methods of animals from insects and ticks with a new composition remains relevant. The goal of the work was to determine the insecto-acaricidal efficacy of the preparation, producer Brovapharma LTD, Ukraine – “Ciflur” (active substance – ciflutrin) in laboratory and production conditions. Materials and methods. The acaricidal efficacy of the preparation “Ciflur” was determined on the starvation ticks of the species Ixodes ricinus in the laboratory of the parasitology department, Kharkiv State ZooVeterinary Academy. Insecto-acaricidal efficacy of “Ciflur” was determined on shorthaired outbred dogs in the conditions of Municipal Enterprise “Center of the reference with animals”, Kharkiv. Parasitological, morphological, biochemical and statistical methods of research were used. Results of research and discussion. The absence of the knockdown effect and expressed 100% acaricidal, soft and stable action of “Ciflur” on the most common species of parasitiformes ticks Ixodes ricinus were established during the study of acaricidal action of “Ciflur” in vitro. The expressed insecto-acaricidal effect of “Ciflur” against fleas and Ixodidae ticks have established for 29 days in production conditions in dogs infested with those parasites. After applied to the dogs’ skin the investigated preparation did not cause local irritation and allergic reaction. Morphological and biochemical indices of dogs’ blood of the experimental group before, and after application of the preparation on the skin were within in physiological limits. In addition to a slight increase in the number of red blood cells (by 1.7%), hemoglobin content (by 5.0%), thrombocytes (by 6.8%) and leukocytes (by 17.7%). The absence of negative influence of active substance – ciflutrin have confirmed in other experiments with laboratory and other animal species. Conclusions and prospects for further research. The expressed acaricidal effect of “Ciflur” on ticks Ixodes ricinus in vitro without knockdown effect and insecto-acaricidal effect on fleas and Ixodidae ticks, which parasitize on dogs have confirmed. Insecto-acaricidal effect lasted 29 days (EE = 100%). Morphological and biochemical indices of blood during the experiment were within in physiological limits. The obtained research results represent value for practicing veterinary specialists to conform the high mild insecto-acaricidal effect of preparation. In the future, it remains interesting to study the effectiveness of the “Ciflur” in other species of animals.
Authors and Affiliations
Yuriy Prykhodko, Alexey Mazannyy, Olga Nikiforova, Viktor Byrka
Keywords
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- EP ID EP406141
- DOI 10.31073/vet_biotech32(2)-53
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