Lower significant rate of etomidate-induced myoclonus for procedural sedation in emergency department of a tertiary care hospital
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 2
Abstract
Background: Etomidate drug is commonly used for procedural sedation in the emergency department (ED). The incidence rate of etomidate-induced myoclonus is 33%. Aims and Objectives: In this study, we aimed to contradict that etomidateinduced myoclonus is less significant than the reported incidence rate. Materials and Methods: This prospective study was performed between June 2016 and November 2016 in the ED of Amrita Institute of Medical Sciences, a tertiary care hospital. In the ED, procedural sedation was carried out by the physician. Adult patients receiving etomidate were enrolled for the study. Results: The presence of myoclonus was noticed, and its duration was reported using the myoclonus scale. A total of 166 (116 males and 50 females) patients enrolled in the ED for procedural sedation with etomidate were taken. The dose administered was 0.3 mg/kg. Myoclonus was observed in 4 (2.4%) of 166 sedations. The mean age was observed to be male and female. During procedural sedation, etomidate-induced myoclonus in ED was less significant than the reported values. Conclusion: From this, we came to the conclusion that the incidence to occur myoclonus with administration of etomidate is less when compare with other ED studies.
Authors and Affiliations
Ashly Alexander Fernandez, Neethu C M
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