MAGNESIUM SUPPLEMENTATION IN CARDIOVASCULAR DISEASES : A SYSTEMATIC REVIEW
Journal Title: Advance Research Journal of Multidisciplinary Discoveries - Year 2018, Vol 27, Issue 27
Abstract
OBJECTIVES: The aim of this study was to clarify the role of Mg2+ in diseases linked to cardiovascular risks. METHODS: A retrospective systematic review of the Medical Literature Analysis and Retrieval System Online and Latin American (MEDLINE) and Caribbean Literature in Health Sciences (LILACS) databases was performed. The following keywords were used for queries: “magnesium supplementation,” “diabetic,” and “lipid profile.” The inclusion criteria for the selection of papers were as follows : original articles or systematic reviews with and without meta-analyses, published between January 2007 and April 2017. Studies that were unrelated to magnesium replacement and cardiovascular function as well as case reports were excluded. RESULTS: Initially, 472 articles were obtained. After applying the inclusion and exclusion criteria, 13 articles were evaluated. Overall, Mg2+ supplementation had a favorable effect on glycemic and lipid indexes in patients with diabetes and/or pre-diabetes. Two studies demonstrated that Mg2+ did not have a significant effect on laboratory test results. In these studies, 62.5% of patients had uncontrolled hbA1c and dyslipidemia, 41% were obese, and 82% had HOMA-IR ≥ 2.5. CONCLUSION: Mg2+ supplementation may contribute to reductions in the risks of cardiovascular diseases. However, owing to the conflicting results, additional complementary studies are needed, not only to improve our understanding of the beneficial pathways involving Mg2+, but also to facilitate the development of robust guidelines for clinical practice.
Authors and Affiliations
Ricardo Silva Tavares, Barbara Rocha Gonçalves 2 , Breno Oliveira de Assis 3 , Emílio Ernesto Garbim Júnior 4 , Jullyana Egito Peixoto Costa
Keywords
Related Articles
- EP ID EP379572
- DOI -
- Views 83
- Downloads 0
LEADERSHIP STYLE AS A PREDICTOR OF EMPLOYEES’ MOTIVATION AND COMMITMENT: EMPIRICAL EVIDENCE FROM SERVICE ORGANIZATION IN NIGERIA
This study focused on Leadership Style, Employee Motivation and Commitment: Empirical Evidence from a Consolidated Organization in a Meltdown Economy. The study took a descriptive survey approach. The study covered a pop...
Literary Satire and its Impact on Public Opinion Direction (Iran and Iraq as Model).
In this research, in order to design a literary satire model and its effect on the guidance of the general public, the views of the experts have been used. Satire writers usually benefit from literary language that is bl...
The Effect of Personality Traits and Burnout Levels in Trinity School of Medicine Students
Overwhelming negative stress can lead to burnout in medical students, which can cause a decrease in academic performance. Several factors can play a role, such as personality, work/school environment, and home life. Pers...
Groundwater Flow Mechanism at a proposed mining site in South-western Sierra Leone
Dry mining of titanium group minerals have been introduced in Sierra Leone aimed at replacing dredging, which has been characterized by serious environmental challenges. Considering the importance of keeping the ore dry...
AGRICULTURAL DEVELOPMENT MANAGEMENT IN NIGERIA : MAXIMIZING NIGERIAN YOUTH POPULATION THROUGH AGROPRENEURSHIP
This paper is on agricultural development management: calling on youths to return to the farm with Orumba North L.G.A as the case study. The study adopted a survey approach and a five point likert scale was used to elici...