MICROSPONGE AS A NOVEL DRUG DELIVERY SYSTEM
Journal Title: Int J of Pharm Rev& Res - Year 2014, Vol 4, Issue 3
Abstract
Microsponges are porous microspheres, biologically inert particles that are made of synthetic polymers and the particles serve to protect the entrapped drug compound from physical and environmental degradation. It is a unique technology for controlled release of topical agents, oral as well as pharmaceutical products which consisting of microporous beads having the size range of 10-25μ in diameter. It has a self sterilizing capacity due to its small pore size where bacteria cannot penetrate into it. These can be prepared by liquid – liquid suspension polymerization and quasi emulsion solvent diffusion method .The prepared microsponges can be characterized for particle size analysis, entrapment efficiency, true density, dissolution studies, and compatibility studies.
Authors and Affiliations
Mansurelahi SK , P. Koteswari , P. Srinivasa Babu
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