EFFICACY OF SUBLINGUAL MISOPROSTOL IN TERMINATION OF EARLY PREGNANCY FAILURE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2014, Vol 3, Issue 23
Abstract
[b]INTRODUCTION:[/b] Nearly 20% of all confirmed pregnancies end in spontaneous abortion. Misoprostol’s use in early pregnancy failure is varied and dose and route are not well established. [b]AIM: [/b]To study the efficacy of sublingual misoprostol in causing expulsion of products of conception in early pregnancy failure. [b]METHODS[/b]: Women with an ultrasound diagnosis of early pregnancy failure, less than 12 weeks gestation were included in the study. Tablet Misoprostol 600 mcg was given six hourly sublingually for 3 doses. All observations were noted and analyzed. [b]RESULTS:[/b] Mean gestational age was 7.946+1.2 weeks. Mean induction abortion interval was 18.241+1.2 hours. Women with gestational age six to eight weeks had least mean induction-abortion interval time of 17.38+2. Mean dose required was 1564mcg.Efficacy of protocol was 92.85% in achieving complete abortion. [b]CONCLUSION:[/b] The regime had 92.85% efficacy, acceptability (90%) and few side effects. Thus by using a lower dose and appropriate interval between two doses (six hours), the side effects were lessened with high efficacy.
Authors and Affiliations
Nupur Hooja, Nandaram Seervi, Asha Verma, Sunita Himani, Kusum Malviya, Rekha Moolchandani, Andaleeb Fatima, Sapna Aseri
Keywords
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- EP ID EP148722
- DOI 10.14260/jemds/2014/2778
- Views 92
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