METFORMIN LOWERS C-REACTIVE PROTEIN LEVELS AND IMPROVES THE MODIFIED BRIEF PAIN INVENTORY SCORES IN A WOMAN WITH ENDOMETRIOSIS – ASSOCIATED CHRONIC PELVIC PAIN: A CASE REPORT AND LITERATURE REVIEW
Journal Title: International Journal of Pharmaceutical Development & Technology - Year 2014, Vol 4, Issue 2
Abstract
Endometriosis is associated with low health-related quality of life and its incidence in the world is not decreasing, at least, in the developed economies. The aim of this case-report is to bring to the fore the beneficial effects of the insulin sensitizer, metformin, in endometriosis-associated chronic pelvic pain. Metformin lowered C-reactive protein levels and attenuated pain symptoms in a 48-year old woman diagnosed with endometriosis refractory to NSAIDs and hormone pills. The effect of metformin in endometriosis-associated chronic pelvic pain may be due to its anti-inflammatory and anti-oestrogenic effects and it warrants being further explored since endometriosis has no specific remedy at present.
Authors and Affiliations
Oriaifo SE , Oriaifo NI
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