NANOSUSPENSION OF A DRUG AND ITS BIOLOGICAL ACTIVITYA REVIEW
Journal Title: Int J of Pharm Rev& Res - Year 2016, Vol 6, Issue 2
Abstract
ABSTRACT With the modern technologies, a large number of drugs have been discovered which have better efficiency but their clinical applications are restricted due to poor solubility. Nearly 40% of the drugs have poor solubility. Poor water solubility has become a leading challenge for formulation of these compounds. Poor solubility is generally associated with poor bioavailability. Nanosuspension has the potential to overcome this issue. This review article outlines various techniques involved for preparation of nanosuspension and the enhancement of biological activities of drug when formulated into nanosuspension. Key words: Nanosuspension, Solubility of drug, Dissolution rate
Authors and Affiliations
Sharamol AR, Smitha K Nair, Anish John, K. Krishnakumar, Dineshkumar B*
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