The Effects Of Neem (Azadirachta Indica) Leaves Extracts, On Some Haematological Indices Of Wistar Rats
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2013, Vol 3, Issue 8
Abstract
The effects of water and methanol extracts of Neem (Azadirachta Indica) leaves were studied in male Wister rats following treatment with 20 % w/w and 30% w/w equivalent of water and methanol extracts of Neem leaves incorporated into rat diet and administered orally for 90 days. The control group had normal diet and water ad libitum. The result showed that PCV of the control group was significantly lower than that of the treated groups at p<0.001. 30% w/w equivalent of neem leaves (C2) significantly increased the PCV (p<0.001) of treated rats. This is consistent with the little or no toxicity observed in Neem extracts.There was no significant variation between the mean TLC of the control and the neem treated groups at P > 0.05. The findings suggest relative safety of the Neem extracts.
Authors and Affiliations
Ndodo N. D, Anuka J. A, Esomonu U. G
Keywords
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