Neurodiagnostic Evaluation of a Child with First Complex Febrile Seizure
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2016, Vol 5, Issue 2
Abstract
Background: Febrile seizure is the most common type of childhood seizure and complex febrile seizure has been associated with the risk of epilepsy. The neurodiagnostic evaluation of a child with first CFS is still unclear. Aim & Objective: To assess the clinical characteristics and diagnostic evaluation of children aged 1 month to 5 years presenting with first Complex Febrile Seizure (CFS) and to determine the utility of various investigations in a case of first CFS. Material and Methods: A prospective study was conducted in the pediatric department of a tertiary hospital. Fortynine children aged 1 month-5 years with first CFS fulfilling the inclusion criteria were enrolled in the study over duration of 8-months. All the cases were evaluated with complete blood count, serum calcium, serum electrolytes, Electroencephalography (EEG), CT/MRI and lumbar puncture. Results: The investigation results were analyzed with respect to different CFS parameter like type of seizure (focal or generalized) and duration of seizure(less than or more than 15 minutes). Upper respiratory tract infection is the main cause of febrile seizure. The duration of CFS did not vary according to the underlying cause. Serum calcium levels are found to be lower in children with complex febrile seizure. All children with CFS, whether focal or multiple generalized, whether of long or short duration, had a normal EEG. Children who had prolonged focal and multiple generalized seizures had abnormal neuroimaging but it was not statistically significant. Conclusion: We conclude from our study that a child with first CFS may not need EEG and neuroimaging as a diagnostic evaluation test. Hypocalcemia can be identified in these children and can be corrected to stop the seizure. Further studies are needed on a large series of children with first CFS to form guidelines for their neurodiagnostic evaluation.
Authors and Affiliations
Arpita S Thakker , Krishna A. Shetye
Deep Vein Thrombosis with First Episode Catatonia: A Case Report
Catatonia is a medical emergency condition with varied causative factors. Subsequent medical complications of catatonia put the patient to high risk of morbidity and mortality. Earlier studies show mortality rates up...
India's Quest towards Food Security
Serous Microcystic Adenoma of Pancreas
Serous Microcystic Adenoma of Pancreas (SMCA) is rare tumor of exocrine pancreas. It has striking predilection for elderly women and consists of small cysts surrounding central stellate scar. Histologically cysts are l...
Study of Lipid Peroxidation and Antioxidant Status in Preeclampsia
Background: Preeclampsia is a pregnancy specificsyndrome, a leading cause of maternalfetalmorbidity and mortality. Free radicals leadto lipid peroxidation which is destructive innature and has been suggested as an aetiol...
Aspergilloma of Infra Orbital Nerve in an Immunocompetent Female: A Case Report
Aspergilloma of the paranasal sinus is a non-invasive form of aspergillosis. We report a 50 year old female with chief complaints of swelling in left infra orbital area without involving maxillary sinus. Computed tom...