Neuroprotective effect of Prunusaviumon on cerebral ischemic stroke in rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 6
Abstract
In this study we use anthocyanins which have both COX-2 inhibitory action and antioxidant activity. Anthocyanins are richly concentrated as pigments in berries. They belong to class of flavonoids, they are water soluble vacuolar pigments that may appear red, purple or blue according to PH. Anthocyanins obtained from berries have therapeutic uses in cancer, aging, and neurological diseases, inflammation, diabetes, bacterial infections, fibrocystic diseases the present work is aimed at evaluating the cyclooxygenase-II inhibitory activity and antioxidant activity of anthocyanins obtained from Prunusaviumin on cerebral ischemic stroke model in rat.
Authors and Affiliations
Gowtham Kumar K, Revena Siddappa D, Janardhan M, Vara Prasad S, Shaik Jilani
Phytochemical evaluation of Cassia tora, Caesalpinia bonducela, Tecoma capensis
In the present study, an attempt was made to investigate phytochemical evaluation of Cassia tora, Caesalpinia bonducela, Tecoma capnensis. The crude drug powder extracts of the leaves of the above plants were taken for...
STUDY OF THE ANALGESIC ACTIVITY OF METHANOLIC EXTRACT OF JASMINE ROOT (Jasminum sambac)
The present study was done to evaluate analgesic activity of methanolic extract of root of Jasmine (Jasminum sambac Linn Aiton). Methanolic extract of root of Jasmine was given in the dose of 200 and 400 mg/kg in Wiste...
A Study on the Antihypertensive Activity of MuktaVati (Ayurvedic Preparation) In Deoxycorticosterone acetate (DOCA) salt Induced Hypertension in Rats
Mukta vati, an ayurvedic formulation is being routinely used to treat cardiovascular ailments like hypertension. However, so far its antihypertensive effect has not been validated in any animal model of hypertension. T...
RECENT TRENDS IN SCOPE AND OPPORTUNITY OF CLINICAL RESEARCH IN INDIA
Clinical Research is one of the most knowledge-intensive industry. It is complete biography of drug from its inception in the lab to its introduction to the consumer market and beyond. Any molecule is identified is sub...
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE DETERMINATION OF CEFDINIR IN BULK AND CAPSULE DOSAGE FORM
A simple, specific, accurate, rapid, inexpensive isocratic Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) method was developed and validated for the quantitative determination of Cefdinir in pharmaceut...