NIFTP: A Critical Pathologist View
Journal Title: Otolaryngology – Open Journal - Year 2017, Vol 3, Issue 1
Abstract
In the last two years, there has been an interesting discussion on NIFTP (Non-invasive folicular Thyroid neoplasm papillary-like nuclear features), the previous encapsulated folicular variant of papillary thyroid carcinoma (EFVPTC). The study of Nikiforov et al,1 laid the foundations of this new discovery, which are: a. The morphological features, i.e., the follicular growth pattern and nuclear features of papillary thyroid carcinoma (PTC); b. Lack of invasion, which separates this tumor from invasive FVPTC; c. Clonal origin determined by finding a driver mutation, which indicates that the lesion is biologically a neoplasm; and d. A very low risk of adverse outcome when the tumor is non-invasive.
Authors and Affiliations
Sydney Correia Leão
Keywords
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- EP ID EP546224
- DOI 10.17140/OTLOJ-3-137
- Views 159
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