NIOSOMAL DRUG DELIVERY SYSTEM-A REVIEW
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2012, Vol 2, Issue 4
Abstract
Niosomes are microscopic non-ionic surfactant vesicles formed by the self assembly of non-ionic surfactant. Niosomal drug delivery poses a promising novel drug delivery approach. Niosomes and liposomes have similar physical properties but differ in the chemical nature. Niosomal vesicle is formed by non-ionic surfactants whereas liposomal vesicles of lipids. Niosomes are superior to liposomes because of higher chemical stability of surfactants than lipids. This review article focuses on the concept of niosomes, advantages and disadvantages, composition, method of preparation, factors influencing the niosomal formulation and characterization, application of niosomes. Niosomes can be utilized in the treatment of several diseases like Psoriasis, leishmaniasis, cancer, migraine, Parkinson etc. Niosomes can be used as diagnostic aid. Various methods of niosomal administration include intramuscular, intravenous, peroral and transdermal. Niosomal technology is widely used in cosmetics. Still researchers have to focus a lot on the commercial utility of niosomes in drug delivery.
Authors and Affiliations
Harini Chowdary Vadlamudi, M. Sevukarajan
Keywords
Related Articles
- EP ID EP222235
- DOI -
- Views 127
- Downloads 0
ISOLATION AND STRUCTURAL ELUCIDATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITIES COMPOUNDS FROM CANTHIAM COROMENDELICUM
Abstract The present study deals with the identifying a Squalene from medicinal plants for pharmaceutical application. Squalene was isolated from Canthiam coromendelicum using soxhlet apparatus. Methanol is a good solven...
Anthelmintic activity of root of Benincasa hispida (Petha)
The present study was undertaken to evaluate anthelmintic activity of crude aqueous, Petroleum ether, chloroform and methanol extracts of Benincasa hispida (Petha) root using Pheretima posthuma as test worms. Single conc...
THE COMPARATIVE FREE RADICAL SCAVENGING EFFECT OF FICUS RELIGIOSA, AEGLE MARMELOS AND BUTEA MONOSPERMA
Abstract Natural products have played crucial role in drug discovery and development. They are capable ofcombating free radicals mediated diseases. The most important of these bioactive constituents of natural products o...
THE TRADITIONAL USES AND PHARMACOLOGICAL ACTIVITIES OF MUCUNA PRURIENS (L)DC: A COMPREHENSIVE REVIEW
Abstract Medicinal plants have served as a constant source of medicaments, which have a great efficacy and demand for the treatment of various diseases. One of the plants, that deserve attention is Mucuna pruriens. The p...
In Vitro Study Of Indirect Mechanism of Plant Growth Promotion
Nine isolates of soil bacteria were tested in vitro. Parameters assessed were HCN production, volatile compound production, production of non-volatile diffusible metabolite, protease enzyme production, antagonistic effec...