Non HDL-C as the Primary Target for LipidLowering Therapy: Moving beyond LDLCentric Management
Journal Title: Indian Journal of Cardio Biology & Clinical Sciences - Year 2015, Vol 2, Issue 1
Abstract
The value of lowering low-density lipoprotein cholesterol (LDL-C) is widely known with a large number of studies demonstrating benefit of LDL-C lowering in a wide range of patient populations. Accordingly, LDL-C has been the focus of lipid lowering therapy for a long period. However, recent data suggest that non-high density lipoprotein cholesterol (non-HDL-C) may be a better target for lipid management than LDL-C. Unlike LDL-C, non-HDL-C includes all atherogenic particles present in blood and therefore provides more complete estimation of cardiovascular risk, esp. in patients with atherogenic dyslipidemia or those already on statin therapy. Further, measurement of non-HDL-C is simple, no extra blood test is required and there is no need for fasting sampling.
Authors and Affiliations
Manish Bansal
Keywords
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