Orbital Metastasis An Analysis of Nine Cases And Review of Literature
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Aim: To analyze nine cases of orbital metastasis with review the literature for incidence, presentation, evaluation and discuss their multidisciplinary management. Materials and Methods: Retrospective study of nine patients between Jan 2012- March 2015 Results: Out of nine consecutive patients with orbital metastasis treated in three year at the department of neurosurgery and neuro-ophthalmology, six patients (75%) were 60 years or older and two were less than 60 years at diagnosis. M: F ratio was 2:1 (M=6, F=3). These patients presented with proptosis in eight (88.8%), pain in four (44.4%), restriction of eye movement in six (66.6%) patients and vision loss in two (22.2%). All these patients presented primarily with orbital symptoms without known primary tumor. Metastatic adeno carcinoma (n=4) was most common histology followed by adenoid cystic carcinoma of salivary gland (n=2), malignant lymphoma, papillary carcinoma of thyroid and malignant osteosarcoma was present in 1 patient each.Over a mean follow-up of eighteen months, seven (77.7%) patients had orbital wall metastasis related systemic involvement and one case (11.1 %) remained free of systemic involvement after chemo. for lymphoma. Three (33.3%) patients had recurrence following surgery within six months. Conclusions: Orbital metastasis is rare and in 1/3 of patients presents as initial presentation with unknown primary. Gastro-intestinal tract, lungs, breast and kidney are most common cancers frequently metastases to orbit. Management of orbital metastasis depends on the outcome of primary disease and overall clinical condition of the patient. The prognosis of these tumors is variable depending on the tissue diagnosis.
Authors and Affiliations
Kamlesh Singh Bhaisora, Rabi Narayan Sahu, Amit Kumar Singh, Ruchi Tomer, Pradeep Sharma, Jayesh Shardhara, Vikas Kanaujia, Kuntal Kanti Das, Anant Mehrotra, Arun Kumar Srivastava, Awadhesh Kumar Jaiswal, Sanjay Behari
Keywords
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- EP ID EP594945
- DOI 10.9790/0853-1604079396.
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