ormulation and Evaluation of Clarithromycin Extended Release Tablets
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2009, Vol 1, Issue 3
Abstract
The Present study to investigate the formulation development of orally administrable Clarithromycin delayed release tablet. Clarithromycin tablet was designed for the delaying the release to prolong the duration of drugaction with the help of various polymers like Microcrystalline Cellulose, HPMC K4M, HPMC K5M, HPMC 6CPS, PEG 6000 with different additives are used for the trial and error method. The prepared tablets showngood dissolution data. The preliminary results from this study suggest that tablets prepared from MCC, HPMC 6CPS and PEG 6000 can be used to incorporate antibiotics like Clarithromycin and may be effective when administered orally in the stomach against H. pylori.
Authors and Affiliations
Mahalingan K. , Rajarajan S. , Beny Baby , Sree Harsha N.
Keywords
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