Overutilization of proton pump inhibitors and H2 receptor antagonists in hospitalized medical patients
Journal Title: Cumhuriyet Medical Journal - Year 2017, Vol 39, Issue 2
Abstract
Objective: The aim of the study was to determine the frequency of the use of proton pump inhibitors (PPI) and histamine-2 receptor antagonists (H2RA), which are widely used drugs, in the medical wards. Method: We retrospectively retrieved medical records of the patients who were hospitalized between January 1st and December 31th, 2010 in a tertiary care university hospital internal medicine wards and medical intensive care unit (MICU); one fourth of the cases who used a H2RA or a PPI drugs were randomly selected for the study. Results: In 2010, half of 4730 patients who admitted to internal medicine wards was ordered a H2RA or a PPI. Of these, 556 patients (25.5%) were evaluated. Majority of the patient (76%) were on PPI. While 90.3% of the patients used a PPI in wards, 74.8% of the patients used a H2RA in the MICU (p<0.001). Sixty-one percent (58/95) of patients who were transferred from the MICU to wards were switched from a H2RA to a PPI without a specific reason. Before admission, 8% of patients was on PPI and 5% on H2RA but at discharge, utilization significantly increased, 79% for PPI and 21% for H2RA (p<0.001). Conclusions: There is a high rate of acid suppressive therapy usage among hospitalized patients and similarly high rate of prescription at discharge. Further studies are required to evaluate the appropriateness of the utilization of these drugs.
Authors and Affiliations
Nursel Çalık Basaran, Lale Özışık, Zhaleh Emaratpardaz, Mine Durusu Tanrıover, Serife Gül Öz
Keywords
Related Articles
- EP ID EP238825
- DOI 10.7197/223.v39i29491.316370
- Views 80
- Downloads 0
Treatment strategies in advanced Parkinson’s disease: Review of the literature
Parkinson’s disease (PD) is a chronic, neurodegenerative disorder affecting basal ganglia, dopamine-secreting cells in the pars compacta region of the substantia nigra, in particular. It commonly affects people above the...
Rare vascular malformation of the scalp : Sinus pericranii
Sinus pericranii (SP) is a very rare venous anomaly and characterized by communication of pericranial varicose venous structures with dural sinus. In this case, we present the multimodality imaging Doppler ultrasonograph...
Littler Flap: A reliable option in soft tissue defects of different fingers
Objective: Finger soft tissue defects are common following trauma, burn, and contracture release. Heterodigital neurovascular island flap is one of the important flaps used for this purpose. However, it is generally used...
Recommendations of 5th-grade Medical Faculty students about clinical anatomy course
Objective: The data gathered objectively, and the information which is evidence-based is essential in evaluating both the sufficiency and the efficiency of medical education. Especially the feedback of students insights...
MRI assessment after reduction in developmental dysplasia of hip
Objective: In this study, the effectiveness of magnetic resonance imaging (MRI) in patients with developmental dysplasia of the hip (DDH) after reduction was examined. Method: Forty-two hips of 31 patients treated betwee...