Paclitaxel and Carboplatin in Elderly Patıents with Advanced Non-Small Cell Lung Cancer
Journal Title: Journal of Clinical and Analytical Medicine - Year 2012, Vol 3, Issue 3
Abstract
Aim: In this study, the safety and tolerability of paclitaxel and carboplatin (PC) regimen in elderly patients with advanced non-small cell lung cancer (NSCLC) was investigated. Material and Method: Elderly patients (ages ≥70 years) who received PC for stage III (n=11) or IV (n=34) NSCLC were evaluated retrospectively. Results: There were 43 males and 2 females, with a median age of 75.5 (range, 70-82). The response rate was 40%. The median overall survival time and progression-free survival time was 13 months and 8.5 months, respectively. One-year survival rate was 51%. Treatment was well tolerated by the patients. The most frequent side effect observed was grade 3 or 4 neutropenia (57.7%). There was no treatmentrelated death. Discussion: PC regimen may be a good alternative for the treatment of elderly patients with advanced NSCLC.
Authors and Affiliations
Özkan Kanat, Erdem Çubukcu, Sinem Çubukcu, Savas Aksoy, Mustafa Canhoroz Canhoroz, Oya Karadağ, Nihan Alkış , Osman Manavoğlu
Keywords
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- EP ID EP145576
- DOI : 10.4328/JCAM.705
- Views 113
- Downloads 0
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