Performance of Methods for Handling Missing Categorical Covariate Data in Population Pharmacokinetic Analyses
Journal Title: The AAPS Journal - Year 2012, Vol 14, Issue 3
Abstract
The online version of this article (doi:10.1208/s12248-012-9373-2) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Ron J. Keizer, Anthe S. Zandvliet, Jos H. Beijnen, Jan H. M. Schellens, Alwin D. R. Huitema
Keywords
Related Articles
- EP ID EP681242
- DOI 10.1208/s12248-012-9373-2
- Views 83
- Downloads 0
Microdialysis of large molecules
Microdialysis has been used in many tissues, including skin, brain, adipose tissue, muscle, kidney, and gastrointestinal tract, to recover low-molecular mass endogenous mediators, metabolites, and xenobiotics from the in...
Joint Model of Iron and Hepcidin During the Menstrual Cycle in Healthy Women
The online version of this article (doi:10.1208/s12248-016-9875-4) contains supplementary material, which is available to authorized users.
Antitumor Activity of Gemcitabine Can Be Potentiated in Pancreatic Cancer through Modulation of TLR4/NF-κB signaling by 6-Shogaol
The online version of this article (doi:10.1208/s12248-013-9558-3) contains supplementary material, which is available to authorized users.
Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges
Various drug delivery approaches can be used to maximize therapeutic efficacy and minimize side effects, by impacting absorption, distribution, metabolism, and elimination (ADME) of a drug compound. For those drugs with...
The effect of alkylpolyglycoside surfactants on the crystallization of spray-dried salbutamol sulphate: a gravimetric near-infrared spectroscopy study
This study monitored the effect of a series of structurally related surfactants on the crystallization of amorphous salbutamol sulphate. Amorphous salbutamol sulphate was prepared by spray drying from a solution in water...