Perioperative transfusion strategies for patients with rare coagulation factor deficiency
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 10
Abstract
Objective To discuss the perioperative blood transfusion strategy of patients with hereditary coagulation factor deficiency through the perioperative blood coagulation management of a patient with coagulation factor Ⅺ deficiency and hemangioma of knee joint. Methods Coagulation factor activity test and gene test were used to confirm the patients with coagulation factor Ⅺ antecedent deficiency. Perioperative bleeding risk assessment, thromboela-stogram(TEG) and coagulation factors detection were performed to detect the coagulation status of the patients. 400 mL fresh frozen plasma was transfused before surgery and first day after surgery, 200 mL daily for 3 days thereafter. Results The level of APTT was controlled from 97.1 s before operation to 36.9 s after operation. There was no obvious bleeding during operation, and the wound healed well after operation. Conclusion In the situation of lack of commercial coagulation factors, transfusion of blood products such as fresh frozen plasma can significantly improve the coagulation function and reduce the risk of intraoperative bleeding in patients with hereditary coagulation factor deficiency during perioperative period.
Authors and Affiliations
Zhengxin SUO, Li WANG, Yingying NIU, Chunyan HUANG
Keywords
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- EP ID EP749834
- DOI 10.13303/j.cjbt.issn.1004-549x.2024.10.005
- Views 51
- Downloads 0
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