Pertussis: treatment goals and prevention options
Journal Title: Актуальна інфектологія - Year 2018, Vol 6, Issue 1
Abstract
The article deals with the questions of rational therapy and immunoprophylaxis of pertussis. It is shown that antibiotics can suppress cough only in incubational period and at prodromal stage as a result of B.pertussis eradication. At the spasmodic stage of pertussis, the main target of therapy is prevention of hypoxia but not suppression of the cough or causative agent eradication. The article highlights importance of hyperleukocytosis as one of the therapy targets at pertussis in young children, through leukapheresis or exchange blood transfusions. One of the methods to decrease morbidity of pertussis is implementation into vaccination schedule the obligatory revaccination of older children and adults.
Authors and Affiliations
V. V. Mavrutenkov, S. A. Kramarov
Keywords
Related Articles
- EP ID EP273510
- DOI 10.22141/2312-413x.6.1.2018.125630
- Views 79
- Downloads 0
Mechanisms of Action of Probiotics based on Bacillus subtilis
The bacterium B.subtilis is one of the most promising probiotics studied in recent decades. Mechanisms of its probiotic action are associated with the synthesis of antimicrobial agents, increasing of non-specific and sp...
Multiple organ lesions in Lyme disease
The article presents the results of clinical studies of 112 patients diagnosed with Lime disease at its different stages. The analysis of polyorganic lesions in patients with this disease has shown a significant percenta...
Wissler — Fanconi Subsepsis as a Result of Persistent Streptococcal Infection
The article presents the clinical case data, demonstra-ting the difficulties in clarifying the origin of the disease in a young child. Difficulty of diagnosis is caused by the lack of specific clinical manifestations of...
The Role of Clostridium Perfringens in the Syndrome of Intestinal Affection in Children and Possibilities of Drug Correction
The article showed the features of clostridiosis course, caused by Clostridium perfringens, in children of different age groups taking into account the dose of pathogen in feces and pathogenetically grounded possibilitie...
Case of Lyme borreliosis in a child
Lyme borreliosis (synonym: Lyme disease) is an infectious transmissible natural focal disease, the causative agents of which are spirochetes, and carriers — ixodid ticks. The first cases of Lyme borreliosis in Ukraine ar...