PHARMACEUTICAL STUDIES OF ATENOLOL BRANDS: INTERCHANGEABILITY BETWEEN ATENOLOL (100 MG) TABLETS BRANDS MARKETED IN LIBYA
Journal Title: Innoriginal: International Journal Of Sciences - Year 2016, Vol 3, Issue 3
Abstract
Hypertension is the most widely distributed cardiovascular diseases in Libyan regions. Atenolol is one of most used β-blockers in Libya as the first line in treatment of hypertension. Therefore, In Libya there are several companies interested to import and distribute many Atenolol brands. The objective of this study was to evaluate the quality of five commercial Atenolol products available on the Libyan market. We carried out a survey of all Atenolol tablet products and assessed their quality. To assess quality, all productsof Atenolol such as: Atenolol tablets, ActavisUnited Kingdom, Totamol tablets WOCKHARDT , United Kingdom, Atenolol Normon Spain,Atenolol Film Coated tablets, BRISTOL, United Kingdom and Hypoten tablets, HIKMA Amman–Jordanwere subjected for the survey includes ten community and hospital pharmacies and volunteers. Our survey was including : Atenolol drug order , Pharmaceutical company sales, Atenolol drug cost, Atenolol drug prescription and Atenolol drugPurchase.Based on our testing procedure, the data of our survey 80-90%, 40-60% and 40-50% of Atenolol tablets, Actavis, Atenolol Film Coated tablets and Totamol tablets respectively are more requested and desired in Libyan drug market. Also, our data revealed 80% and 90% of volunteers said that, Film Coated tablets and Atenolol tablets, Actavis respectively are more cheaper than other brands. About 80 % to Atenolol tablets, Actavis and 70% to Film Coated tablets are more requested and desired to the patients or customers. Our survey represented about 80% and 70% of pharmacy purchases are belonged to Atenolol tablets, Actavis & Atenolol Normon respectively.
Authors and Affiliations
Abdulrhman. A. Akasha, Somaia . A . Elsaedi
MULTIVARIATE CHEMOMETRIC MODELS USED FOR THE ANALYSIS OF RAFOXANIDE IN PRESENCE OF ITS ALKALINE DEGRADATION PRODUCT
Objective: Development and validation of three simple, accurate and precise chemometric models for the determination of rafoxanide in the presence of its alkaline degradation product without preliminary separation. Metho...
A PROMISING APPROACH TO ENHANCE SOLUBILITY AND BIOAVAILABILITY BY SELF EMULSIFYING DRUG DELIVERY SYSTEM: A BRIEF REVIEW
Objective: The formulation of self-emulsifying drug delivery system of drugs is to enhance the solubility and bioavailability. More than 40% of available drugs exhibit poor water solubility, resulting in unsatisfactory o...
DEVELOPMENT AND VALIDATION OF A NEW RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CEFIXIME AND LINEZOLID IN TABLET DOSAGE FORMS
A simple, precise, stability indicating new RP-HPLC method was developed and validated for the Simultaneous determination of Cefiximeand Linezolid. In this method separation of liquid was done by using column Inertsil OD...
VALIDATED SPECTROFLUORIMETRIC METHOD FOR THE DETERMINATION OF DORZOLAMIDE HYDROCHLORIDE IN ITS PURE FORM AND PHARMACEUTICAL FORMULATIONS VIA DERIVATIZATION WITH 4-CHLORO-7-NITROBENZO-2-OXA-1, 3- DIAZOLE (NBD-CL)
Objectives: Simple spectrofluorimetric method was applied and validated for the determination of dorzolamide hydrochloride in its pure form and pharmaceutical formulations. Method: Based on nucleophilic substitution reac...
NUMERICAL INVESTIGATION OF THERMALLY COUPLED CATALYTIC MICROREACTORS USING COMPUTATIONAL FLUID DYNAMICS
Ammonia decomposition thermally coupled with methane catalytic combustion in catalytic microreactors for hydrogen production was studied numerically, using a two-dimensional computational fluid dynamics model. The effect...