POSSIBILITIES OF CURRENT METHODS OF ULTRASONOGRAPHY IN DIAGNOSTIC OF LIVER STEATOSIS IN PATIENTS WITH CHRONIC HEPATITIS C
Journal Title: Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал - Year 2012, Vol 68, Issue 2
Abstract
Development of liver steatosis influence fibrosis progression in patients with chronic hepatitis C. Noninvasive methods of steatosis detection are under the development. The aim of our study was an improvement of liver steatosis detection in patients with chronic hepatitis C by the way of detection and evaluation of mean grey value of liver parenchyma, indices of peripheral microcirculation (vascularisation index, flow index and vascularisation-flow index) in tree-dimensional regime with usage of power Doppler (3D+PD). 96 patients with confirmed diagnosis of chronic hepatitis C were included. All patients underwent general clinical- laboratory investigation and complex ultrasound investigation in 2D and 3D+PD regimes. All patients were divided into two groups: I group – 56 patients with CHC and liver steatosis, II group – 40 patients with chronic hepatitis C without sings of liver steatosis. Control group consist of 38 healthy volunteers. In patients with CHC and concomitant liver steatosis were detected character changes in 3D+PD regime such as decrease in indices of peripheral microcirculation and slight increase in mean grey value of liver parenchyma compared with control group, in constant to patients without steatosis, who develop severe increase of mean grey value. Presence of such criteria as decrease of peripheralmicrocirculation indices and slight increase of mean gray value of liver parenchyma can be used as additional sign of liver steatosis in patients with CHC. Usage of modern methods of ultrasonography, such as 3D-visualisation with Power Doppler sonography are rather informative for estimation of liver steatosis, fibrosis and peripheral microcirculati
Authors and Affiliations
K. Pronyuk
Keywords
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