Pregnancy and asymptomatic bacteriuria- A study from a tertiary care teaching hospital, Hyderabad
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
IntroductionAsymptomatic bacteriuria is found in 2 to 10 of pregnant women Complications like acute pyelonephritis postpartum UTI hypertension anemia prematurity low birth weight babies and prenatal death may occur if untreated Hence early detection and treatment are of considerable importanceMaterials and MethodsA crosssectional study was conducted for a period of one year A clean catch midstream urine sample was collected from pregnant women as a part of routine antenatal screening The samples were processed according to standard microbiological techniques wet mount examination gram staining glucose test paper culture and antibiotic susceptibility testingResultsOf the 200 samples received from the study group 2814 were culture positive The prevalence of culture positivity was more in the third trimester 194The predominant organisms isolated were gram negative bacteria like Escherichia coli 357 and Klebsiella spp 285 Ecoli and Klebsiella showed variable resistance to fluoroquinolones cephalosporins aminoglycosides betalactam and betalactam inhibitor combination However the isolates of Ecoli were sensitive to carbapenams and polymixins Isolates of Klebsiella spp were sensitive to PolymixinsThe predictive accuracy of different screening tests with culture was calculated The sensitivity specificity positive predictive value negative predictive value of grams staining is more compared to urine wet mount examination and urine test paper method in early detection of bacteruriaConclusionEarly detection and treatment for asymptomatic bacteriuria is of considerable importance as 40 of asymptomatic cases develop into pyelonephritisThe choice of antibiotic should be based on urine culture stage of gestation clinical data and the characteristics of the antibioticKeywordsAsymptomatic bacteriuria Antenatal women prevalence Glucose test paper Urine culture Wetmount examination Gram staining Perinatal outcomes
Authors and Affiliations
Yamini Kura, Swathi Akula, Sandeep Kumar Tipparthi, HRV Rajkumar
Keywords
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- EP ID EP485871
- DOI 10.18231/2581-4761.2018.0039
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