Presentation of Ocular Surface Squamous Neoplasia, Its Demographic, Histopathological Analysis
Journal Title: International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS) - Year 2015, Vol 2, Issue 11
Abstract
Studying of the presentation of Ocular surface squamous neoplasia with analysis of its demographic and histopathological characteristics was the aim of this study. This study is a case series of 38 suspected cases of OSSN presenting at our institute over a period of 24 months. Detailed history and all clinical and demographic parameters were noted. Suspected lesions underwent excision biopsy and histopathological investigation. All the data were analyzed and presented in the form of statistical percentage.For the study ,five discrete variables namely Gender, Laterality, Location, Keratinisation, size and their association with invasive disease was calculated using Chi square test and fishers test. Total 38 cases were included in study. Patients were usually male (71.8%), elderly (63.15% with age>60 years), 32 cases were diagnosed as OSSN. Disease was predominant in rural areas (76.31%) and in occupations with sun exposure i.e. Agriculture (36.8%) & Labourers (39.4%). Most commonly presented as visible mass (63.15%) nodular type (60.52%). Invasive disease was present in 18 cases (56.25%), large size of tumour was associated with invasive disease (two tailed p Value: 0.01 by fisher’s exact test). Histopathological evidence of solar damage was present in most of the cases.It was concluded that OSSN is common in bundelkhand region. OSSN occurs in sun damaged ocular surface, usually presents as a limbal nodule in rural, elderly men. Larger tumour size was associated with invasive lesions. Large tumours should be treated with great surgical care and should be closely followed up.
Authors and Affiliations
Kumar Jitendra, Sahay Renu, Gujarathi Atul M, Shams Misba
Keywords
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