PREVALENCE OF HELICOBACTER PYLORI INFECTION IN PATIENTS WITH ACUTE PEPTIC ULCER BLEEDING IN A TERTIARY CARE HOSPITAL IN MANIPUR
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 50
Abstract
BACKGROUND Helicobacter pylori (H. pylori) is one of the commonest causes of peptic ulcer disease. Diagnosis and successful H. pylori eradication is important to prevent complications like recurrent peptic ulcer bleeding (PUB). Aims and Objectives- This study aims to evaluate the prevalence of H. pylori infection in patients with acute PUB. MATERIALS AND METHODS This study was carried out from September 2015 till August 2018 in patients with PUB admitted at JNIMS hospital who underwent endoscopic procedures in a prospective manner. RUTs were performed by taking mid-antral biopsy specimen. Statistical Analysis- Baseline characteristics were presented as mean±standard deviation (SD) for continuous variables and as a frequency (percentage) for all variables. Chi square and two tailed Fischer’s exact test were used where applicable. RESULTS Four hundred and sixty patients were included, of which duodenal ulcer bleeding comprised of 85% (391), gastric ulcer 10.44 % (48) and combined gastric and duodenal ulcer in 4.56% (21). RUT was positive in 419 patients (91.08%). Of the 48 gastric ulcer patients 82.6% (38) had positive RUT and of the 412 duodenal ulcer patients 92.47% (381) had positive RUT. H. pylori infection rates were high in patients with acute peptic ulcer bleeding patients. CONCLUSION This exploratory study showed the importance of actively looking for H. pylori infection in patients with acute peptic ulcer bleeds who are likely to rebleed if not treated with H. pylori eradication regimes.
Authors and Affiliations
Nongthombam Suraj Kumar, Takhellambam Rebika Devi, Konjengbam Ghanachandra Singh
Keywords
Related Articles
- EP ID EP549274
- DOI 10.14260/jemds/2018/1182
- Views 82
- Downloads 0
CARCINOEMBRYONIC ANTIGEN LEVELS AMONG STROKE PATIENTS
BACKGROUND CEA (carcinoembryonic antigen) is mainly associated with malignant conditions, but there is a modest increase in non-malignant conditions such as aging, and atherosclerosis and this study is to find correlatio...
DO PLATELET INDICES PLAY A ROLE WITH RESPECT TO PLATELET COUNT AND INFECTIONS?
BACKGROUND Platelet an essential constituent of blood plays an important role in coagulation, thrombosis, inflammation and maintains the integrity of vascular endothelial cells. Platelet indices like Plateletcrit (PCT),...
CROSS SECTIONAL STUDY REGARDING KNOWLEDGE, ATTITUDE AND AWARENESS AMONG ADOLESCENTS ON HEALTH, NUTRITION AND PSYCHOSOCIAL ASPECTS
[b] OBJECTIVE[/b]:To determine the awareness among medical and paramedical adolescent students regarding various aspects like nutrition, health and psychosocial, and to educate them on those issues. [b]MATERIALS...
PATTERN AND OUTCOME OF NEONATAL ADMISSIONS- AN EXPERIENCE FROM A DISTRICT LEVEL SCNU
BACKGROUND Neonatal mortality still continues to be a significant contributor to the infant mortality rate in India. Also the rural-urban gap in the neonatal mortality rate is significant. It is imperative therefore to s...
MANAGEMENT OF CUT-THROAT INJURIES- OUR EXPERIENCES
BACKGROUND Cut-throat injuries of the neck are one of the emergencies encountered in the emergency department. Neck contains multiple vital structures with little anatomic protection from overlying bone, muscle and soft...