Prevalence of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) In Hepatocellular Carcinoma Patients Attending A Cancer Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Purpose: The most common etiological agents for hepatocellular carcinoma (HCC) are hepatitis B virus (HBV) and hepatitis C virus (HCV). The present study was aimed to assess the seroprevalence of hepatitis B surface antigen (HBsAg) and antibodies to HCV among patients with HCC, attending a cancer hospital. Method: A retrospective study of patients with histologically and radiologically proven HCC between July 2014 and April 2016 were evaluated for HBsAg and anti-HCV antibodies by Enhanced Chemiluminescence Immuno Assay (CLIA) method using the VITROS ECi/ECiQ Immunodiagnostic systems. Result: Out of 116 HCC patients, 34 (29.31%) were having HBsAg positivity and HCV positivity was seen in 15(12.93%). Co-infection by HCV and HBV was found in 3 (2.58%) patients. Males are affected more than females and most of them are in their fifth or sixth decade. Alpha feto protein levels were higher in 85(73.27%) of patients and serum aminotransferase levels are higher than the reference range. Conclusion: The high seropositivity of HBV and HCV in HCC suggests their role as the causative agents of Hepatocellular carcinoma.
Authors and Affiliations
Dr. B. Sridevi Chaitanya, Dr. D. Radha Rani
Keywords
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- EP ID EP593725
- DOI 10.9790/0853-1604035861.
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