Prevalence of Meningitis Among Infants with Neonatal Sepsis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background; Neonatal sepsis still forms the most important and serious causes of morbidity and mortality out come in the neonatal periods of infantsespeciallypreterm very low birthweight whom admitted for management in neonatal intensive care units. The morbidityand mortality related to the maturity degree and time of discovered and treatment, there are very high risk of mortality and morbidity due to difficulties in rapid diagnosis as the conformation of NS if blood culture is positive but if the blood culture is negative, the physician cannot differentiate meningitis from sepsis clinically without lumbar puncture and CSF culture and sensitivity. Objectives; The aim of this study to remember the treating physician the incidence of neonatal meningitis among newborns with late-onset sepsis, and to determine whether it is mandatory to perform a lumbar puncture and cerebrospinal fluid (CSF) analysis in all infants of late-onset neonatal sepsis. Study Design; This study was carried out in the Pediatrics department [Neonatal Intensive Care Unit] of Zagazig general and Healthy Insurance Hospitals in Sharika Egyptover 50 neonatal infants(28 females and 22 males) presenting with late-onset neonatal septicemia. All studied neonates were subjected to history taking, clinical examination stressing on points of the clinical sepsis score, routine investigations (complete blood count, C-reactive protein, blood culture), and CSF analysis and culture. Results; All 50 neonatal infants were positive for the clinical sepsis score: 40 cases were positive for the hematological sepsis score and 10 cases out of 50 were positive for CSF culture; among the 10 cases with positive CSF cultures, there were 4 cases (40%) with negative blood cultures Conclusion; There is a high incidence of neonatal meningitis among neonatal infantsdiagnosed neonatal early and late sepsis, the incidence increased toward late onsetsepsis Neonatalmeningitis frequently occurs in the absence of bacteremia. Hence,lumbar puncture and CSF examination is mandatory in all cases with late-onset sepsis
Authors and Affiliations
Saber A. M. El-Sayed, Yasser F Ali, Mostafa M. Ahmady
Keywords
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- EP ID EP256034
- DOI 10.9790/0853-1609047376
- Views 82
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